Implementation of an Interleukin-2 National Registry: an opportunity to improve cancer outcomes
نویسندگان
چکیده
Cancer registries have proven valuable with respect to validating therapeutic safety and drug efficacy, uncovering real-world implementation practices, and their evolution over time. Modern cancer therapeutics are approved as single agents oftentimes compared to the least active approved standard agent in randomized trials. However, the burgeoning diversity and number of drugs introduces a complexity that quickly outstrips the knowledge provided by these pivotal trials. This gap in information is particularly relevant when survival is the primary therapeutic endpoint. In addition, the inherent complexity of the immune response will make registries a particularly important tool in expeditiously understanding solid tumor immunotherapy and patient outcomes.
منابع مشابه
Trend of Breast Cancer Incidence in Iran During A Fifteen-Year Interval According To National Cancer Registry Reports
Introduction: Breast cancer is the most common cancer and cause of cancer-related death in women. Recent years have witnessed dramatic changes in the incidence and mortality rates of breast cancer. Therefore, this study aimed to provide a report of breast cancer incidence trends between 2003 and 2017. Methods: This cross-sectional study examined Iran’s cancer registry reports from 2003 to 2017...
متن کاملHealth Equity in National Cancer Control Plans: An Analysis of the Ontario Cancer Plan
Background National cancer control plans (NCCPs) are important documents that guide strategic priorities in cancer care and plan for the appropriate allocation of resources based on the social, geographic and economic needs of a population. Despite the emphasis on health equity by the World Health Organization (WHO), few NCCPs have ...
متن کاملAssociation of interleukin-1 gene polymorphism with risk of gastric and colorectal cancers in an Iranian population
متن کامل
پیشنهاد یک نظام ملی ثبت تروما برای ایران
Trauma is the fourth cause of death at all age groups with socio-economic costs which caused more than 6 million deaths in the world in 2000. Despite promising trend in improving many aspects of health case and treatment in the last decade in our country, little attention has been paid to the subject of registering trauma on an international standard. Effective practical research specially ...
متن کاملUnderstanding the Role of Public Administration in Implementing Action on the Social Determinants of Health and Health Inequities
Many of the societal level factors that affect health – the ‘social determinants of health (SDH)’ – exist outside the health sector, across diverse portfolios of government, and other major institutions including non-governmental organisations (NGOs) and the private sector. This has created growing interest in how to create and implement public policies which will drive better and fairer health...
متن کامل